Mosquito Borne Disease Information for Laboratories

Physicians have been advised to report selected cases and write orders to have an aliquot of CSF (as mush as feasible) and serum (3ml) sent to the state biological laboratory for suspect cases of aseptic/viral meningitis, encephalitis, and Guillain - Barré syndrome as part of annual seasonal surveillance for West Nile Virus and other arboviral neuroinvasive disease. Guideance

What You Should Do

  • If the clinical diagnosis is known to be encephalitis or Guillain - Barré syndrome, transport an aliquot of CSF (any cell count) and serum specimen to the state biological laboratory according to established procedures.
  • If the patient is 17 years old or older, send any CSF specimen with a cell count of more than 10 cells. Send a serum specimen with the CSF. (If the diagnosis is known to the lab to be a non-infectious condition, such specimens do not need to be sent.)
  • Use the standard state laboratory submission form. Check the box labeled "Arbovirus (WNV)" on the form.
  • Transport specimens on weekdays only. Refrigerate specimens held on weekends and holidays. (If you cannot guarantee arrival by 4 PM on Friday, hold the specimen until the following Monday. You can call the state laboratory if you have questions about shipping on Fridays.)
  • Contact physicians when no order is received so that small volumes of CSF are prioritized and apportioned appropriately for testing.
  • Process tests ordered other than arboviral according to your normal procedure. If a test result in serum or CSF is positive for WNV IgM as reported by a commercial or hospital laboratory and this result is known to you, report the result to the Division of Infectious Disease.
  • Consult the state biological laboratory as necessary.